The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
keratin 19
Isotype
IgG
Molecular Weight
46 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CK 19, CK19, Cytokeratin 19, K19, K1CS, keratin 19, KRT19
Uniprot
P08727
Gene Id
3880
Research Area
Stem Cells, Immunology, Cancer
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)