The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19, one of type I keratins, is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity, KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients.Keratin 19 is a type I cytokeratin. It is a biochemical marker of skin stem cells in vivo and in vitro.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
keratin 19
Isotype
IgG
Molecular Weight
44-50 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CK 19, CK19, Cytokeratin 19, K19, K1CS, keratin 19, KRT19
Uniprot
P08727
Research Area
Stem Cells, Immunology, Cancer
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)