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Home / Primary Antibodies / Monoclonal Antibodies

Cytokeratin 18 antibody

SKU : BHA10802200

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Mfr.No.	FNab02206
Alternative Names	CK18 ; CYK18 ; Cytokeratin18 ; K18 ; keratin18 ; KRT18
Background	Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9K23, and the hair keratins Ha1Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1K8, and the hair keratins, Hb1Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.
Categories	Primary Antibodies
Clonality	monoclonal
Description	Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.
Host	Mouse
Immunogen	keratin 18
Isotype	IgG2a
Molecular Weight	48 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CK 18, CYK18, Cytokeratin 18, K18, keratin 18, KRT18

Uniprot	P05783
Clone No	6E3
Research Area	Cancer, Immunology, Cardiovascular
Weight	48kDa

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, FC, IF, IHC

Description

ELISA ; WB ; FC ; IF ; IHC

Dilution

WB	1:5000-1:50000
IHC	1:600-1:2000
IF	1:20-1:200

Tested Application

WB: 1:5000-1:30000; IHC: 1:500-1:1000; IF: 1:100-1:300

Manual	FNab02206.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802200	FNab02206	100ug	$300		Add to Cart

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