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Home / Primary Antibodies / Polyclonal Antibodies

CYP4F3 antibody

SKU : BHA10802167

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Mfr.No.	FNab02173
Alternative Names	LTB4H
Background	Isoform CYP4F3A: Catalyzes the omega-hydroxylation of leukotriene-B(4), a potent chemoattractant for polymorphonuclear leukocytes, it has low activity for arachidonic acid. Isoform CYP4F3B: Shows arachidonic acid omega-hydroxylase activity by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid(20-HETE)(PubMed:11461919, PubMed:16820285). Has a 30-fold higher Km for leukotriene-B(4) compared with CYP4F3A(PubMed:11461919). Also converts eicosapentaenoate(EPA) to 20-hydroxyeicosapentaenoate(20-OH-EPA)(PubMed:16820285). Acts as a polyunsaturated omega-3 fatty acids hydroxylase: mediates conversion of docosahexaenoate(DHA) to 22-hydroxydocosahexaenoate(PubMed:16820285).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Isoform CYP4F3A: Catalyzes the omega-hydroxylation of leukotriene-B(4), a potent chemoattractant for polymorphonuclear leukocytes, it has low activity for arachidonic acid. Isoform CYP4F3B: Shows arachidonic acid omega- hydroxylase activity by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE) (PubMed:11461919, PubMed:16820285). Has a 30-fold higher Km for leukotriene-B(4) compared with CYP4F3A (PubMed:11461919). Also converts eicosapentaenoate (EPA) to 20-hydroxyeicosapentaenoate (20-OH-EPA) (PubMed:16820285). Acts as a polyunsaturated omega-3 fatty acids hydroxylase: mediates conversion of docosahexaenoate (DHA) to 22- hydroxydocosahexaenoate (PubMed:16820285).
Host	Rabbit
Immunogen	cytochrome P450, family 4, subfamily F, polypeptide 3
Isotype	IgG
Molecular Weight	60 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	LTB4H

Uniprot	Q08477
Gene Id	4051
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802167	FNab02173	100ug	$240		Add to Cart

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