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Home / Primary Antibodies / Polyclonal Antibodies

CYP2F1 antibody

SKU : BHA10802154

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Mfr.No.	FNab02160
Background	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
Categories	Primary Antibodies
Clonality	polyclonal
Description	May be involved in the metabolism of various pneumotoxicants including naphthalene. Is able to dealkylate ethoxycoumarin, propoxycoumarin, and pentoxyresorufin but possesses no activity toward ethoxyresorufin and only trace dearylation activity toward benzyloxyresorufin. Bioactivates 3- methylindole (3MI) by dehydrogenation to the putative electrophile 3-methylene-indolenine.
Host	Rabbit
Immunogen	cytochrome P450, family 2, subfamily F, polypeptide 1
Isotype	IgG
Molecular Weight	46 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	P24903
Gene Id	1572
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab02160.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802154	FNab02160	100ug	$260		Add to Cart

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