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Home / Primary Antibodies / Polyclonal Antibodies

CYP24A1 antibody

SKU : BHA10802145

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Mfr.No.	FNab02151
Alternative Names	CYP24
Background	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1, 25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23- hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
Host	Rabbit
Immunogen	cytochrome P450, family 24, subfamily A, polypeptide 1
Isotype	IgG
Molecular Weight	59 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	24 OHase, CP24, CYP24, CYP24A1, Cytochrome P450 24A1, Cytochrome P450 CC24, P450 CC24, Vitamin D(3) 24 hydroxylase

Uniprot	Q07973
Gene Id	1591
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab02151.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802145	FNab02151	100ug	$240		Add to Cart

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