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Home / Primary Antibodies / Polyclonal Antibodies

CYP1A1 antibody

SKU : BHA10802141

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Mfr.No.	FNab02147
Background	This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Host	Rabbit
Immunogen	cytochrome P450, family 1, subfamily A, polypeptide 1
Isotype	IgG
Molecular Weight	63 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	P04798
Gene Id	1543
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, FC, IF
Description	ELISA ; WB ; IHC ; FC ; IF
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab02147.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802141	FNab02147	100ug	$260		Add to Cart

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