Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
cyclin B2
Isotype
IgG
Molecular Weight
50 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CCNB2, cyclin B2, G2/mitotic specific cyclin B2, HsT17299
Uniprot
O95067
Gene Id
9133
Research Area
Cell Division and Proliferation, Developmental biology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)