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Home / Primary Antibodies / Monoclonal Antibodies

CXCR3B-specific antibody

SKU : BHA10802095

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Mfr.No.	FNab02101
Background	CXCR3(C-X-C chemokine receptor type 3) is a G protein-coupled, seven-transmembrane domain chemokine receptor that is expressed on the surface of a number of cell types, including activated CD4+ and CD8+ T cells, NK and NK-T cells, plasmacytoid dendritic cells, and some B cells(PMID: 16847335). CXCR3 binds and is activated by the three IFN-gamma-inducible chemokines: CXCL9, CXCL10, and CXCL11. Binding of these ligands to CXCR3 has been implicated in regulating T-cell infiltration during inflammation and tissue injury(PMID: 17250586). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms, CXCR3B, mediates the angiostatic activity of CXCR3 ligands and also acts as functional receptor for CXCL4(PMID:12782716). This monoclonal antibody is specific to CXCR3B.
Categories	Primary Antibodies
Clonality	monoclonal
Host	Mouse
Immunogen	chemokine(C-X-C motif) receptor 3
Isotype	IgG1
Molecular Weight	40 kDa +43 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	CD183, CKR L2, CMKAR3, CXC R3, CXCR 3, CXCR3, CXCR3A, CXCR3B, G protein coupled receptor 9, GPR9, IP 10 receptor, IP10 R, Mig R, MigR

Uniprot	P49682
Clone No	6F7
Research Area	Stem Cells, Immunology, Signal Transduction

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:5000

Manual	FNab02101.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802095	FNab02101	100ug	$260		Add to Cart

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