Receptor for the CX3C chemokine fractalkine(CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions(PubMed:9390561, PubMed:23125415). Acts as coreceptor with CD4 for HIV-1 virus envelope protein(in vitro)(PubMed:9726990). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1(PubMed:14607932).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions (PubMed:9390561, PubMed:23125415). Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro) (PubMed:9726990). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1 (PubMed:14607932).
Host
Rabbit
Immunogen
chemokine(C-X3-C motif) receptor 1
Isotype
IgG
Molecular Weight
47 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CMKBRL1, GPR13
Uniprot
P49238
Gene Id
1524
Research Area
Stem Cells, Immunology, Signal Transduction, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)