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Home / Primary Antibodies / Polyclonal Antibodies

CSRP3 antibody

SKU : BHA10802025

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Mfr.No.	FNab02031
Alternative Names	CLP ; MLP
Background	This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Positive regulator of myogenesis. Plays a crucial and specific role in the organization of cytosolic structures in cardiomyocytes. Could play a role in mechanical stretch sensing. May be a scaffold protein that promotes the assembly of interacting proteins at Z-line structures. It is essential for calcineurin anchorage to the Z line. Required for stress-induced calcineurin-NFAT activation (By similarity).
Host	Rabbit
Immunogen	cysteine and glycine-rich protein 3 (cardiac LIM protein)
Isotype	IgG
Molecular Weight	25 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CLP, MLP

Uniprot	P50461
Gene Id	8048
Research Area	Developmental biology, Cardiovascular

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab02031.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802025	FNab02031	100ug	$240		Add to Cart

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