The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues.
Host
Rabbit
Immunogen
cartilage associated protein
Isotype
IgG
Molecular Weight
50 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CASP
Uniprot
O75718
Gene Id
10491
Research Area
Developmental biology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)