Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element(CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Host
Rabbit
Immunogen
cAMP responsive element binding protein 1
Isotype
IgG
Molecular Weight
43-46 kDa
Reactivity
Human, Mouse, Rat, Monkey
Regulatory
RUO
Synonyms
CREB, CREB 1, CREB1
Uniprot
P16220
Gene Id
1385
Research Area
Developmental biology, Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)