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Home / Primary Antibodies / Polyclonal Antibodies

CRCP antibody

SKU : BHA10801949

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Mfr.No.	FNab01955
Background	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).
Categories	Primary Antibodies
Clonality	polyclonal
Description	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa- B through the RIG-I pathway (By similarity). Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.
Host	Rabbit
Immunogen	CGRP receptor component
Isotype	IgG
Molecular Weight	20 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CGRP RCP, CGRP receptor component, CGRPRCP, CRCP, HsC17, RCP, RCP9, RNA polymerase III subunit C9

Uniprot	O75575
Gene Id	27297
Research Area	Developmental biology, Signal Transduction, Metabolism, Cardiovascular, Immunology

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, FC, IP
Description	ELISA ; WB ; IHC ; FC ; IP
Tested Application	WB: 1:1000-1:4000; IP: 1:500-1:2000; IHC: 1:20-1:200

Manual	FNab01955.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801949	FNab01955	100ug	$240		Add to Cart

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