Component of the cleavage factor Im complex(CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping.
Host
Rabbit
Immunogen
cleavage and polyadenylation specific factor 6, 68kDa
Isotype
IgG
Molecular Weight
55-68 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CFIM68
Uniprot
Q16630
Gene Id
11052
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)