Component of the cleavage and polyadenylation specificity factor(CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.
Host
Rabbit
Immunogen
cleavage and polyadenylation specific factor 1, 160kDa
Isotype
IgG
Molecular Weight
160kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CPSF160
Uniprot
Q10570
Gene Id
29894
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)