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Home / Primary Antibodies

Cortactin Antibody

SKU : BHA17102361

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Mfr.No.	F53608
Clonality	Monoclonal
Description	This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Formulation	In ascites with 0.09% sodium azide
Host	Mouse
Immunogen Region	Purified His-tagged Cortactin protein fragment was used to produced this monoclonal Cortactin antibody.
Isotype	IgM
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	Cortactin
Uniprot	Q14247
Clone No	401CT8.6.3

Format	Ascites
Purification	Ascites
Storage	Aliquot the Cortactin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Dilution	Western blot: 1:1000-1:8000

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17102361	F53608	0.1 ml	$379		Add to Cart

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