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Home / Primary Antibodies / Polyclonal Antibodies

Collagen Type IV antibody

SKU : BHA10801838

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Mfr.No.	FNab01844
Background	Type IV collagen is the major structural component of glomerular basement membranes(GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and-9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	collagen, type IV, alpha 2
Isotype	IgG
Molecular Weight	200 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	COL4A2, Collagen alpha 2(IV) chain, Collagen Type IV, collagen, type IV, alpha 2, DKFZp686I14213, FLJ22259

Uniprot	P08572
Gene Id	1284
Research Area	Cancer, Immunology

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC
Description	ELISA ; IHC
Tested Application	WB: 1:200-1:2000; IHC: 1:20-1:200

Manual	FNab01844.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801838	FNab01844	100ug	$240		Add to Cart

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