Type III collagen is a fibrillar forming collagen comprising three a1(III) chains and is expressed in early embryos and throughout embryogenesis. In the adult, type III collagen is a major component of the extracellular matrix in a variety of internal organs and skin. It occurs in most soft connective tissues along with type I collagen. COL3A1 gene encodes type III procollagen. Mutations in this gene are associated with type III and IV Ehlers-Danlos syndrome, and with aortic and arterial aneurysms.(PMID: 9050868; 2445760)
Categories
Primary Antibodies
Clonality
polyclonal
Description
Type III collagen is a fibrillar forming collagen comprising three a1(III) chains and is expressed in early embryos and throughout embryogenesis. In the adult, type III collagen is a major component of the extracellular matrix in a variety of internal organs and skin. It occurs in most soft connective tissues along with type I collagen. COL3A1 gene encodes type III procollagen. Mutations in this gene are associated with type III and IV Ehlers-Danlos syndrome, and with aortic and arterial aneurysms. (PMID: 9050868; 2445760)
Host
Rabbit
Immunogen
collagen, type III, alpha 1
Isotype
IgG
Molecular Weight
140-150 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
COL3A1, Collagen alpha 1(III) chain, Collagen Type III, collagen, type III, alpha 1, EDS4A, FLJ34534
Uniprot
P02461
Gene Id
1281
Research Area
Stem Cells, Signal Transduction
Weight
139kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)