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Home / Primary Antibodies / Polyclonal Antibodies

COCH antibody

SKU : BHA10801818

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Mfr.No.	FNab01824
Alternative Names	COCH5B2
Background	The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Plays a role in the control of cell shape and motility in the trabecular meshwork.
Host	Rabbit
Immunogen	coagulation factor C homolog, cochlin (Limulus polyphemus)
Isotype	IgG
Molecular Weight	Refer to Figures
Reactivity	Human
Regulatory	RUO
Synonyms	COCH5B2

Uniprot	O43405
Gene Id	1690
Research Area	Signal Transduction, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA
Description	ELISA
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100

Manual	FNab01824.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801818	FNab01824	100ug	$240		Add to Cart

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