This gene encodes a protein that binds members of the toll-like receptor protein family and functions as a chaperone to aid in folding and export of these proteins. Alternative splicing results in multiple transcript variants. Naturally occuring readthrough transcription occurs between this locus and the downstream GNMT (glycine N-methyltransferase) gene and is represented with GeneID:107080644.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity).
Host
Rabbit
Immunogen
canopy 3 homolog (zebrafish)
Isotype
IgG
Molecular Weight
38 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CTG4A, ERDA5, PRAT4A, TNRC5
Uniprot
Q9BT09
Gene Id
10695
Research Area
Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)