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Home / Primary Antibodies / Polyclonal Antibodies

CLIC4 antibody

SKU : BHA10801756

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Mfr.No.	FNab01761
Background	Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell- surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical- basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).
Host	Rabbit
Immunogen	chloride intracellular channel 4
Isotype	IgG
Molecular Weight	29 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CLIC4L

Uniprot	Q9Y696
Gene Id	25932
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Manual	FNab01761.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801756	FNab01761	100ug	$240		Add to Cart

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