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Home / Antibodies

Cleaved-PARP-1 (D214) Polyclonal Antibody

SKU : BHA13715159

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABP0027
Alternative Names	PARP1; ADPRT; PPOL; Poly (ADP-ribose) polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly(ADP-ribose) synthase 1
Background	PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, poly(ADP-ribose) polymerase 1 may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Clonality	Polyclonal
Description	Rabbit Anti-Cleaved-PARP-1 (D214) Polyclonal Antibody
Formulation	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen, Liquid solution
Host	Rabbit
Immunogen	Synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220
Immunogen Region	Synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220
Isotype	Rabbit IgG
Molecular Weight	24 KD
Others	Cleaved-PARP-1 (D214) Polyclonal Antibody detects endogenous levels of fragment of activated PARP-1 protein resulting from cleavage adjacent to D214.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Reactivity	Human, Mouse
Tag	Poly (ADP-ribose) polymerase 1
Note	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:50-1:300), IHC-P (1:50-1:300), ELISA (1:20000). Not yet tested in other applications.

Accession Number	P09874
Gene Id	142, 142

Concentration	1 mg/ml, 1 mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen, The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Storage Buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instructions	Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Applications	WB, IF, IHC-P, ELISA

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA13715159	ABP0027	100 uL	$229		Add to Cart

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