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Home / Primary Antibodies / Polyclonal Antibodies

cleaved Caspase 9 antibody

SKU : BHA10801291

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Mfr.No.	FNab01296
Background	This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.This antibody can recognize the pre- and cleaved- caspase 9.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	caspase 9, apoptosis-related cysteine peptidase
Isotype	IgG
Molecular Weight	17kDa/36kDa/46kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	APAF 3, APAF3, Apoptotic protease Mch 6, CASP 9, CASP9, Caspase 9, CASPASE 9c, Caspase9, Caspase-9, ICE LAP6, ICE like apoptotic protease 6, MCH6

Uniprot	P55211
Gene Id	842
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF
Description	ELISA ; WB ; IHC ; IF
Tested Application	WB: 1:200 - 1:200; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Manual	FNab01296.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801291	FNab01296	100ug	$240		Add to Cart

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