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Home / Primary Antibodies / Polyclonal Antibodies

CLASP1 antibody

SKU : BHA10801725

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Mfr.No.	FNab01730
Alternative Names	KIAA0622 ; MAST1
Background	CLASPs, such as CLASP1, are nonmotor microtubule-associated proteins that interact with CLIPs (e.g., CLIP170; MIM 179838). CLASP1 is involved in the regulation of microtubule dynamics at the kinetochore and throughout the spindle (Maiato et al., 2003 (PubMed 12837247)).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
Host	Rabbit
Immunogen	cytoplasmic linker associated protein 1
Isotype	IgG
Molecular Weight	169 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	KIAA0622, MAST1

Uniprot	Q7Z460
Gene Id	23332
Research Area	Cell Division and Proliferation

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IF, IHC, IP, WB
Description	ELISA ; IF ; IHC ; IP ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Manual	FNab01730.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801725	FNab01730	100ug	$240		Add to Cart

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