BIRC2(also known as cIAP1) is a member of the inhibitor of apoptosis protein(IAP) family. The inhibitor of apoptosis(IAP) proteins are a family of anti-apoptotic regulators found in viruses and metazoans. BIRC2 is a nuclear shuttling protein, whose subcellular localization is mediated by the CRM1-dependent nuclear export pathway(PMID: 15265700). This cIAP1 antibody can bind both full length(70kd) and cleaved form(60kd) of the protein.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
baculoviral IAP repeat-containing 2
Isotype
IgG
Molecular Weight
70 kDa, 60 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
API1, BIRC2, C IAP1, cIAP1, Hiap 2, HIAP2, IAP 2, IAP homolog B, IAP2, MIHB, RING finger protein 48, RNF48
Uniprot
Q13490
Research Area
Immunology, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)