CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1.
Host
Rabbit
Immunogen
chromatin accessibility complex 1
Isotype
IgG
Molecular Weight
17 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
CHRAC15
Uniprot
Q9NRG0
Gene Id
54108
Research Area
Epigenetics
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)