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Home / Primary Antibodies / Monoclonal Antibodies

Chk1 antibody

SKU : BHA10801648

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Mfr.No.	FNab01653
Background	HEK1(Checkpoint kinase-1) is also named as CHK1 and belongs to the protein kinase superfamily. It is implicated in a circuit in which it activates checkpoints, DNA repair and proliferating cell nuclear antigen and FANCD2 monoubiquitinylation(PMID:21389083). CHEK1 protects vertebrate cells against spontaneous chromosome missegregation and is required to sustain anaphase delay when spindle function is disrupted by taxol(PMID:17276342). It has 3 isoforms produced by alternative splicing with the molecular mass of 54 kDa, 44 kDa and 50 kDa.
Categories	Primary Antibodies
Clonality	monoclonal
Host	Mouse
Immunogen	CHK1 checkpoint homolog
Isotype	IgG2a
Molecular Weight	50 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CHEK1, Chk1

Uniprot	O14757
Gene Id	1111
Clone No	9F10
Research Area	Developmental biology, Cell Division and Proliferation, Signal Transduction, Metabolism, Cancer

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

Manual	FNab01653.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801648	FNab01653	100ug	$260		Add to Cart

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