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Home / Primary Antibodies / Polyclonal Antibodies

Chk1 antibody

SKU : BHA10801647

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Mfr.No.	FNab01652
Background	The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	CHK1 checkpoint homolog (S. pombe)
Isotype	IgG
Molecular Weight	54 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	O14757
Gene Id	1111
Research Area	Developmental biology, Cell Division and Proliferation, Signal Transduction, Metabolism, Cancer

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF, FC
Description	ELISA ; WB ; IF ; FC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab01652.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801647	FNab01652	100ug	$240		Add to Cart

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