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Home / Primary Antibodies / Polyclonal Antibodies

CHIA antibody

SKU : BHA10801645

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Mfr.No.	FNab01650
Background	The protein encoded by this gene degrades chitin, which is found in the cell wall of most fungi as well as in arthropods and some nematodes. The encoded protein can also stimulate interleukin 13 expression, and variations in this gene can lead to asthma susceptibility. Several transcript variants encoding a few different isoforms have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding.
Host	Rabbit
Immunogen	chitinase, acidic
Isotype	IgG
Molecular Weight	52 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	Q9BZP6
Gene Id	27159
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF
Description	ELISA ; WB ; IHC ; IF
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab01650.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801645	FNab01650	100ug	$260		Add to Cart

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