Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
Host
Rabbit
Immunogen
cystic fibrosis transmembrane conductance regulator(ATP-binding cassette sub-family C, member 7)
Isotype
IgG
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
ABC35, ABCC7, CF, CFTR, CFTR/MRP, MRP7, TNR CFTR
Uniprot
P13569
Gene Id
1080
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)