The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Clonality
polyclonal
Host
Rabbit
Immunogen
CFHR3
Immunogen Region
CFHR3
Isotype
IgG
Molecular Weight
45 kDa
Reactivity
Human, Mouse
Recommended Dilution
IHC: 1:20-1:200
Synonyms
CFHL3, DOWN16, FHR-3, FHR3, HLF4
Uniprot
Q02985
Gene Id
10878
Research Area
Immunology
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:100
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10775.pdf" target="_blank">Data Sheet</ a>