Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11(7-ethyl-10-(4-(1-piperidino)-1-piperidino)-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)- 1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics.
Host
Rabbit
Immunogen
carboxylesterase 3
Isotype
IgG
Molecular Weight
60-62 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
carboxylesterase 3, CES3, ES31
Antigen
CES3
Uniprot
Q6UWW8
Gene Id
23491
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)