Component of the CENPA-CAD(nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex.
Host
Rabbit
Immunogen
centromere protein O
Isotype
IgG
Molecular Weight
34kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
ICEN36, MCM21R
Uniprot
Q9BU64
Gene Id
79172
Research Area
Proliferation, Cell Division
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)