This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins.
Clonality
polyclonal
Host
Rabbit
Immunogen
Complement decay-accelerating factor
Immunogen Region
Complement decay-accelerating factor
Isotype
IgG
Molecular Weight
55 kDa
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000; IF: 1:50-1:200
Synonyms
CD55, CR, CROM, DAF, TC
Uniprot
P08174
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000; IF: 1:50-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10514.pdf" target="_blank">Data Sheet</ a>