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Home / Primary Antibodies / Polyclonal Antibodies

CD45 antibody

SKU : BHA10801479

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Mfr.No.	FNab01484
Alternative Names	B220 ; CD45 ; CD45R ; GP180 ; LCA ; LCA ; Leukocytecommonantigen ; LY5 ; PTPRC ; RPTPC ; T200
Background	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	protein tyrosine phosphatase, receptor type, C
Isotype	IgG
Molecular Weight	190 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	B220, CD45, CD45R, GP180, L CA, LCA, Leukocyte common antigen, LY5, PTPRC, RPTPC, T200

Uniprot	P08575
Gene Id	5788
Research Area	Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Stem Cells, Neuroscience
Weight	147kDa,observed 200kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, WB, FC, IP

Description

ELISA ; IHC ; WB ; FC ; IP

Dilution

WB	1:200-1:1000
IP	1:200-1:1000
IHC	1:100-1:800

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab01484.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801479	FNab01484	100ug	$280		Add to Cart

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