The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Clonality
polyclonal
Host
Rabbit
Immunogen
CD44 molecule
Immunogen Region
CD44 molecule
Isotype
IgG
Molecular Weight
79 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
IHC: 1:20-1:200
Synonyms
LHR, MDU2, MDU3, MIC4
Uniprot
P16070
Gene Id
960
Research Area
Stem Cells, Immunology, Cardiovascular, Cancer
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Application
IHC: 1:20-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10089.pdf" target="_blank">Data Sheet</ a>