The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
sialophorin
Isotype
IgG
Molecular Weight
130 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
GALGP,SPN
Uniprot
P16150
Gene Id
6693
Research Area
Stem Cells, Immunology, Signal Transduction, Cancer
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)