Receptor for TNFSF5/CD40LG. Transduces TRAF6-and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Host
Rabbit
Immunogen
CD40 molecule, TNF receptor superfamily member 5
Isotype
IgG
Molecular Weight
22kd,30kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
Bp50;CDW40;TNFRSF5;p50
Uniprot
P25942
Research Area
Immunology, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)