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Home / Primary Antibodies / Polyclonal Antibodies

CD4 antibody

SKU : BHA10801470

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Mfr.No.	FNab01475
Background	This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. (Microbial infection) Acts as a receptor for human immunodeficiency virus-1 (PubMed:2214026, PubMed:16331979, PubMed:9641677). Down-regulated by HIV-1 Vpu (PubMed:17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed:7909607).
Host	Rabbit
Immunogen	CD4 molecule
Isotype	IgG
Molecular Weight	51 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CD4, CD4 molecule, CD4mut,T-cell surface glycoprotein CD4,T-cell surface antigen T4/Leu-3

Uniprot	P01730
Gene Id	920
Research Area	Developmental biology, Cancer, Immunology, Signal Transduction
Weight	51kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IP

Description

ELISA ; WB ; IP

Dilution

WB	1:500-1:5000
IP	1:200-1:2000
IHC	1:50-1:500

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab01475.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801470	FNab01475	100ug	$260		Add to Cart

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