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Home / Primary Antibodies / Polyclonal Antibodies

CD206 antibody

SKU : BHA10801437

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Mfr.No.	FNab01442
Background	CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains(responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia. This antibody recognizes the intracellular carboxy-terminal part of CD206 and MRC1L1.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	mannose receptor, C type 1
Isotype	IgG
Molecular Weight	166 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CD206, CLEC13D, Macrophage mannose receptor 1, Mannose receptor, mannose receptor, C type 1, MMR, MRC1

Uniprot	P22897
Research Area	Immunology, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, FC
Description	ELISA ; WB ; IHC ; FC
Tested Application	WB: 1:200-1:2000; IHC: 1:50-1:200

Manual	FNab01442.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801437	FNab01442	100ug	$260		Add to Cart

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