CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This antibody recognizes the intracellular carboxy-terminal part of CD206 and MRC1L1.
Clonality
monoclonal
Host
Mouse
Immunogen
CD206
Immunogen Region
CD206
Isotype
IgG2a
Molecular Weight
170 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:1000-1:4000; IP: 1:200-1:1000
Synonyms
CD206, CLEC13D, Macrophage mannose receptor 1, Mannose receptor, mannose receptor, C type 1, MMR, MRC1
Uniprot
P22897
Gene Id
4360
Clone No
5E3
Research Area
Immunology
Form
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:1000-1:4000; IP: 1:200-1:1000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09812.pdf" target="_blank">Data Sheet</ a>