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Home / Primary Antibodies / Polyclonal Antibodies

CD146/MCAM antibody

SKU : BHA10801423

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Mfr.No.	FNab01428
Alternative Names	CD146 ; MCAM ; MUC18 ; CellsurfaceglycoproteinMUC18 ; CellsurfaceglycoproteinP1H12 ; Melanomacelladhesionmolecule ; Melanoma-associatedantigenA32 ; Melanoma-associatedantigenMUC18
Categories	Primary Antibodies
Clonality	polyclonal
Description	CD146, also known as melanoma cell adhesion molecule (MCAM) or MUC18, originally identified as a biomarker of melanoma progression, is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily (PMID: 8378324). Structurally, it consists of five Ig domains, a transmembrane domain, and a cytoplasmic region. In normal adult tissue, CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis, and has been used as marker of circulating endothelium cells (CECs) (PMID: 19356677).
Host	Rabbit
Immunogen	melanoma cell adhesion molecule
Isotype	IgG
Molecular Weight	113-120 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CD146, MCAM, MUC18, Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, Melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18

Uniprot	P43121
Gene Id	4162
Research Area	Developmental biology, Cardiovascular, Immunology, Cancer, Stem Cells
Weight	72kDa,Observed 120kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, WB, IP

Description

ELISA ; IHC ; WB ; IP

Dilution

WB	1:1000-1:10000

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab01428.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801423	FNab01428	100ug	$240		Add to Cart

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