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Home / Primary Antibodies / Polyclonal Antibodies

CD14 antibody

SKU : BHA10810355

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Mfr.No.	FNab10397
Background	Coreceptor for bacterial lipopolysaccharide(PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide(LPS)(PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response(PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway(PubMed:16880211).
Clonality	polyclonal
Host	Rabbit
Immunogen	CD14 molecule
Immunogen Region	CD14 molecule
Isotype	IgG
Molecular Weight	50-55 kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:200-1:2000
Synonyms	CD14, CD14 molecule

Uniprot	P08571
Gene Id	929
Research Area	Stem Cells, Immunology, Signal Transduction, Cancer

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:200-1:2000

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10397.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810355	FNab10397	100ug	$280		Add to Cart

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