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Home / Primary Antibodies / Polyclonal Antibodies

CD133 antibody

SKU : BHA10801413

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Mfr.No.	FNab01418
Alternative Names	AC133 ; AntigenAC133 ; CD133 ; CORD12 ; MCDR2 ; MSTP061 ; PROM1 ; PROM11 ; PROM11 ; 2 ; 3
Background	This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	CD133, also known as PROM1 (prominin-1) or AC133, belongs to the prominin family. CD133 is a transmembrane glycoprotein with an NH2-terminal extracellular domain, five transmembrane loops and a cytoplasmic tail. The expression of CD133 has been reported in hematopoietic stem cells, endothelial progenitor cells, neuronal and glial stem cells, suggesting the potential role of CD133 as a cell surface marker of adult stem cells. CD133 has also been reported as a marker of cancer stem cells in various human tumors.
Host	Rabbit
Immunogen	prominin 1
Isotype	IgG
Molecular Weight	115 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	AC133, Antigen AC133, CD133, CORD12, MCDR2, MSTP061, PROM1, PROM1 1, PROM1 1, 2, 3, PROM1 1, 2, 3, 5, 7, PROM1 1, 6, 7, PROM1 2, PROM1 2, 3, 4, 5, prominin 1, Prominin like protein 1, PROML1, RP41, STGD4

Uniprot	O43490
Gene Id	8842
Research Area	Stem Cells, Immunology, Cancer, Neuroscience
Weight	120kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:200-1:2000
IHC	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab01418.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801413	FNab01418	100ug	$240		Add to Cart

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