Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor(CD4 being the primary receptor) for HIV-1 R5 isolates. (Microbial infection) Acts as a receptor for human immunodeficiency virus-1/HIV-1.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates. (Microbial infection) Acts as a receptor for human immunodeficiency virus-1/HIV-1.
Host
Rabbit
Immunogen
chemokine(C-C motif) receptor 5
Isotype
IgG
Molecular Weight
45 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CMKBR5
Uniprot
P51681
Gene Id
1234
Research Area
Immunology, Signal Transduction, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)