Required for assembly of dynein regulatory complex(DRC) and inner dynein arm(IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella(PubMed:21131974). Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer(nm) repeat length and arrangements of components in cilia and flagella(By similarity). Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39(PubMed:21131974).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella (PubMed:21131974). Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39 (PubMed:21131974).
Host
Rabbit
Immunogen
coiled-coil domain containing 40
Isotype
IgG
Molecular Weight
90-100 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
KIAA1640
Uniprot
Q4G0X9
Gene Id
55036
Research Area
Epigenetics
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)