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Home / Primary Antibodies / Polyclonal Antibodies

CBX4 antibody

SKU : BHA10801326

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Mfr.No.	FNab01331
Categories	Primary Antibodies
Clonality	polyclonal
Description	E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131. Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Host	Rabbit
Immunogen	chromobox homolog 4 (Pc class homolog, Drosophila)
Isotype	IgG
Molecular Weight	85 kDa
Reactivity	Human, Mouse
Regulatory	RUO

Uniprot	O00257
Gene Id	8535
Research Area	Developmental biology, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IF, WB
Description	ELISA ; IF ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP : 1:50 - 1:200

Manual	FNab01331.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801326	FNab01331	100ug	$240		Add to Cart

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