Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor(LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
Host
Rabbit
Immunogen
chromobox homolog 1(HP1 beta homolog Drosophila)
Isotype
IgG
Molecular Weight
25 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CBX
Uniprot
P83916
Gene Id
10951
Research Area
Epigenetics, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)