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Home / Primary Antibodies / Monoclonal Antibodies

Caveolin-1 antibody

SKU : BHA10801309

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Mfr.No.	FNab01314
Background	Caveolin-1 is a protein that in humans is encoded by the CAV1 gene.The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.
Categories	Primary Antibodies
Clonality	monoclonal
Host	Mouse
Immunogen	caveolin 1, caveolae protein, 22kDa
Isotype	IgG1
Molecular Weight	22 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	caveolin 1, CAV1

Uniprot	Q03135
Gene Id	857
Clone No	0H8
Research Area	Signal Transduction, Metabolism, Cardiovascular, Immunology, Stem Cells

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

Manual	FNab01314.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801309	FNab01314	100ug	$260		Add to Cart

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